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Medchemexpress LLC 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine | 1627503-67-6 | MFCD28168043 | 99.5% | 419.52 g/mol | C25H29N3O3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1671210MG

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LDN-214117 is a selective small-molecule inhibitor of Activin receptor-like kinase 2 (ALK2/ACVR1) used in research to modulate BMP/TGF-β signaling. It is orally active, shows brain penetration, and demonstrates nanomolar potency against ALK2, making it suitable for biochemical and cellular studies and kinase target validation.

  • Nanomolar potency against ALK2 (IC50 24 nM).
  • High selectivity over related receptors (for example, >100-fold vs ALK5).
  • Purity 99.54% by HPLC.
  • Available as solid (including 5 mg and 10 mg) and as a 10 mM solution in DMSO.
  • Suitable for biochemical and cellular BMP/TGF-β pathway studies.
  • Certificate of analysis and safety data sheet available.
  • Recommended storage: powder at -20°C; solutions at -80°C.

Catalog No. 50-002-89256


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