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  6. Sigma Aldrich 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid 

Sigma Aldrich 1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetraacetic Acid

Catalog No. 8673450MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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86-734-250MG 50 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent.It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64Cu radioisotope.DOTA can be activated with N-hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.It can form complexes with gadolinium for application as MRI contrast agents.Metal complexes of DOTA-peptide conjugates can be used as therapeutic radiopharmaceuticals.

Specifications

CAS 5574-97-0
Melting Point 151°C to 154°C
Molecular Formula C16H38NO4P
Linear Formula (CH3CH2CH2CH2)4N[OP(OH)2O]
MDL Number MFCD00064526
Quantity 50 g
Molecular Weight (g/mol) 339.45 g/mol
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