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Medchemexpress LLC 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine, monohydrochloride | 152-53-4 | 99.9% | 50 MG
Supplier: Medchemexpress LLC HY12784A50MG
Cycloguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor that blocks the folate metabolic pathway, affecting nucleotide synthesis and interfering with DNA replication. It inhibits DHFR in Plasmodium, making it useful in malaria research, and potently inhibits DHFR in human cancer cells, demonstrating anticancer activity by blocking the transcriptional activity of STAT3.
- Dihydrofolate reductase (DHFR) inhibitor
- Blocks the folate metabolic pathway
- Affects nucleotide synthesis and DNA replication
- Useful in malaria research
- Inhibits DHFR in human cancer cells
- Blocks transcriptional activity of STAT3
- Demonstrates anticancer activity
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