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Medchemexpress LLC 1-(4-fluorophenyl)-N-((2-(methylsulfonyl)pyridin-4-yl)methyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxamide | 1220026-26-5 | 99.7% | 425.44 g·mol⁻¹ | C20H16FN5O3S | 10MG
SDP

Supplier:  Medchemexpress LLC HY12475910MG

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CCR1 antagonist 9 is a potent, selective small-molecule antagonist of the CC chemokine receptor 1 (CCR1) intended for laboratory research. It inhibits CCR1-mediated calcium flux with an IC50 of 6.8 nM, blocks CCR1 chemotaxis of THP-1 cells (IC50 28 nM), and shows hERG inhibition at higher concentrations (IC50 30 μM).

  • Potent CCR1 antagonist with low-nanomolar activity in calcium flux assay.
  • Demonstrated inhibition of CCR1 chemotaxis in THP-1 cells.
  • High reported purity (≈99.7%).
  • Chemical formula C20H16FN5O3S and molecular weight ~425.44 g·mol⁻¹.
  • Typically supplied as a solid or as DMSO solutions for in vitro studies.
  • Storage recommendations for powder and solutions to preserve stability.

Catalog No. 50-002-35816


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