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Medchemexpress LLC 1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione | 1160247-92-6 | 99.9% | 10 MG
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Supplier:  Medchemexpress LLC HY1215710MG

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VU 0238429 is a selective positive allosteric modulator of the muscarinic acetylcholine receptor subtype M5 (mAChR5), with an EC50 of approximately 1.16 μM. It is used as a research tool to probe M5-mediated GPCR signaling and neuronal pharmacology.

  • Molecular formula: C17H12F3NO4.
  • Molecular weight: 351.28 g/mol.
  • CAS number: 1160247-92-6.
  • Purity: ~99.9% by HPLC.
  • Solubility: ≥150 mg/mL in DMSO; ≥2.5 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline for in vivo formulations.
  • Target: muscarinic acetylcholine receptor M5 (mAChR5).
  • EC50: ~1.16 μM at M5; >30 μM at M1 and M3 indicating selectivity.
  • Storage: powder -20°C (long term), 4°C (short term); solutions -80°C (up to 6 months).
  • Quantity: supplied as a 10 mg solid.

Catalog No. 50-002-31536


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