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Medchemexpress LLC 1-[(4-phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione | 1208222-39-2 | MFCD22683818 | 99.4% | 397.35 g/mol | C22H14F3NO3 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY10765110MM 1ML

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VU 0365114 is a selective muscarinic acetylcholine receptor (mAChR) M5 positive allosteric modulator used in research to probe M5 receptor pharmacology and β-cell insulin secretion. It displays an EC50 of 2.7 μM at M5 and EC50 >30 μM at M1-M4, enabling selective modulation of M5-mediated responses.

  • Selective positive allosteric modulation of mAChR M5.
  • EC50 2.7 μM at M5 and EC50 >30 μM at M1-M4, indicating high selectivity.
  • Enhances acetylcholine-stimulated insulin secretion in human β-cells.
  • Available as solid or as a 10 mM solution in DMSO for flexible application.
  • High purity suitable for biochemical and cellular assays.

Catalog No. 50-002-44527


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