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Medchemexpress LLC 1,5-Methano-8H-pyrido[1,2-a]diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-methyl-,(1R,5S)- | 486-86-2 | 204.27 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN044310MM/1ML

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N-Methylcytisine (Caulophylline) is a tricyclic quinolizidine alkaloid recognized for its hypoglycaemic, analgesic, and anti-inflammatory properties. It acts as a selective ligand for nicotinic acetylcholine receptors in the central nervous system, showing a high affinity (Kd = 50 nM) for nAChR from squid optical ganglia. This compound is intended for research use only.

  • Exhibits hypoglycaemic, analgesic and anti-inflammatory activities.
  • Acts as a selective ligand of nicotinic receptors of acetylcholine.
  • Shows high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR).
  • Ameliorates symptoms of DSS-induced colitis in mouse models.
  • Reduces concentrations of TNF-α, IL-1β, and IL-6.
  • Inhibits p-NK-κB p65 expression in colon tissue.

Catalog No. 50-003-89731


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