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Medchemexpress LLC 1-(6,7-dichloro-9-(1-methyl-1H-pyrazol-3-yl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)-2-hydroxyethanone | 2369751-07-3 | MFCD34368516 | 99.2% | C17H16Cl2N4O2 | 10MG
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Supplier:  Medchemexpress LLC HY13391610MG

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G140 is a small-molecule research inhibitor of cyclic GMP-AMP synthase (cGAS) used to investigate innate immune and inflammatory signaling. It is potent against human cGAS (IC50 14.0 nM) and shows activity against mouse cGAS (IC50 442 nM), and is provided as a high-purity compound for in vitro studies.

  • Potent, selective inhibition of cGAS in human assays.
  • IC50 14.0 nM for human cGAS and 442 nM for mouse cGAS.
  • High purity suitable for biochemical and cell-based assays.
  • Supplied as a small-molecule solid for in vitro research.
  • Enables study of the cGAS-STING pathway and inflammatory responses.

Catalog No. 50-002-58707


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