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Cayman Chemical 1 7-DImethylurIc AcId 50mg
SDP

Supplier:  Cayman Chemical 1958450 MG

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A synthetic derivative of staurosporine that inhibits a variety of kinases including Akt protein kinase C (IC50 30 nM) PDK1 (IC50 6 nM) and cyclin-dependent kinases (IC50s 300-600 nM for Cdk1 and Cdk2) arrests tumor cells in the G1/S phase of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase Chk1 (IC50 7 nM) leading to apoptosis

Catalog No. 50-298-1722


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