1-(Heptafluorobutyryl)imidazole, 97%

Description

CAS: 32477-35-3 | C7H3F7N2O | 264.103 g/mol

1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.

Solubility
Miscible with chloroform and methanol.

Notes
Hygroscopic and air sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 32477-35-3
• Molecular Formula: C7H3F7N2O
• Molecular Weight (g/mol): 264.103
• MDL Number: MFCD00014503
• InChI Key: MSYHGYDAVLDKCE-UHFFFAOYSA-N
• Synonym: n-heptafluorobutyrylimidazole, 1-heptafluorobutyryl imidazole, heptafluorobutyrylimidazole, n-heptafluorobutyryl imidazole, hfbi, 1-perfluorobutyryl imidazole, 2,2,3,3,4,4,4-heptafluoro-1-1h-imidazol-1-yl butan-1-one, 1-2,2,3,3,4,4,4-heptafluoro-1-oxobutyl-1h-imidazole, 2,2,3,3,4,4,4-heptafluoro-1-imidazol-1-yl butan-1-one, 1h-imidazole, 1-2,2,3,3,4,4,4-heptafluoro-1-oxobutyl
• PubChem CID: 94431
• IUPAC Name: 2,2,3,3,4,4,4-heptafluoro-1-imidazol-1-ylbutan-1-one
• SMILES: C1=CN(C=N1)C(=O)C(C(C(F)(F)F)(F)F)(F)F

• Melting Point: 10°C to 13°C
• Density: 1.49
• Boiling Point: 160°C to 162°C
• Flash Point: 77°C (170°F)
• Refractive Index: 1.385
• Quantity: 5 g
• Beilstein: 4488026
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with chloroform and methanol.
• Formula Weight: 264.1
• Percent Purity: ≥98%
• Chemical Name or Material: 1-(Heptafluorobutyryl)imidazole

Safety and Handling

Hazard Category	H227-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335-H227 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
EINECSNumber	251-063-8
TSCA	No
Recommended Storage	Store at -20°C; Store under Argon

SDS

RUO – Research Use Only