Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000412908

Medchemexpress LLC 1-Hexadecanaminium, N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]dimethyl bromide | 553-08-2 | 99.9% | 5 MG
SDP

Supplier:  Medchemexpress LLC HYB12465MG

Encompass_Preferred

Thonzonium bromide is an antibacterial and monocationic surface-active agent. It inhibits RANKL-induced osteoclast formation and bone resorption in vitro, preventing LPS-induced bone loss in vivo. It also inhibits proton transport in a dose-dependent manner, blocking the activation of NF-κB, ERK, and c-Fos, and the induction of NFATc1. This compound disrupts F-actin ring formation in mature osteoclasts, and has shown protective effects in a murine model of LPS-induced calvarial osteolysis.

  • Antibacterial agent
  • Monocationic surface-active agent
  • Inhibits RANKL-induced osteoclast formation and bone resorption in vitro
  • Prevents LPS-induced bone loss in vivo
  • Inhibits proton transport
  • Blocks RANKL-induced activation of NF-κB, ERK, and c-Fos
  • Disrupts F-actin ring formation
  • Activates human PXR in HepG2 cells

Catalog No. 50-004-12908


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.