1-Iodo-3,5-bis(trifluoromethyl)benzene, 97+%

Description

CAS: 328-73-4 | C8H3F6I | 340.007 g/mol

3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-bis(trifluoromethyl)pheny1- magnesium iodide was prepared from 1-iodo-3,5- bis(trifluoromethyl)benzene. Monodeprotected masked hexayne was not particularly stable and hence was used directly without purification in a Sonogashira coupling with 1-iodo-3,5-bis(trifluoromethyl)benzene to provide mono-aryl-end-capped masked hexayne.

Solubility
Slightly soluble in water.

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.

Specifications

Chemical Identifiers

• CAS: 328-73-4
• Molecular Formula: C8H3F6I
• Molecular Weight (g/mol): 340.007
• MDL Number: MFCD00040837
• InChI Key: VDPIZIZDKPFXLI-UHFFFAOYSA-N
• Synonym: 1-iodo-3,5-bis trifluoromethyl benzene, 3,5-bis trifluoromethyl iodobenzene, 1,3-bis trifluoromethyl-5-iodobenzene, 3,5-bis trifluoromethyl-1-iodo benzene, benzene, 1-iodo-3,5-bis trifluoromethyl, 1-iodo-3,5-di trifluoromethyl benzene, 3-5-di trifluoromethyl iodobenzene, pubchem1056, acmc-209hwp
• PubChem CID: 630970
• IUPAC Name: 1-iodo-3,5-bis(trifluoromethyl)benzene
• SMILES: C1=C(C=C(C=C1C(F)(F)F)I)C(F)(F)F

• Density: 1.919
• Boiling Point: 62°C to 64°C (12 mmHg)
• Flash Point: 74°C (165°F)
• Refractive Index: 1.4645
• Quantity: 5 g
• Beilstein: 2461627
• Solubility Information: Slightly soluble in water.
• Formula Weight: 340.01
• Percent Purity: ≥97%
• Chemical Name or Material: 1-Iodo-3,5-bis (trifluoromethyl)benzene

Safety and Handling

Hazard Category	H227-H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335-H227 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.
Precautionary Statement	P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only