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Medchemexpress LLC 1-Methylcytosine | 1122-47-0 | 125.13 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYW006395

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1-Methylcytosine is a methylated form of the DNA base cytosine. It is utilized as a nucleobase of hachimoji DNA, where it forms a pair with Isoguanine. It has been observed to exhibit weak antiproliferative activity against cervical cancer cells and can be utilized in cervical cancer research.

  • Weakly inhibits proliferation of human cervical cancer HeLa cells with an IC50 value of 12 μM.
  • Shows no antiproliferative activity against human tumor cell lines such as MiaPaCa-2, SW620, MCF-7, and H460 (IC50 >100 μM for all).
  • Functions as a nucleoside antimetabolite/analog.
  • Involved in cell cycle/DNA damage pathway.

Catalog No. 50-004-46683


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