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Medchemexpress LLC 1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- | 2413020-56-9 | 99.9% | 476.53 | 25 MG

Supplier: Medchemexpress LLC 25MGHY161573
BAY-593 is an orally active GGTase-I inhibitor. It can block YAP1/TAZ signaling in animals and has antitumor activity.
- Orally active GGTase-I inhibitor
- Blocks YAP1/TAZ signaling in animals
- Exhibits antitumor activity
- Inhibits proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively
- Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple negative breast cancer xenotransplantation mouse models
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