1-Propylphosphonic acid cyclic anhydride, 50+% soln. in ethyl acetate, Thermo Scientific Chemicals

Description

1-Propylphosphonic acid cyclic anhydride is used in the synthesis of N-acyloxythiazole-2(3H)-thiones. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Propylphosphonic acid cyclic anhydride is used in the synthesis of N-acyloxythiazole-2(3H)-thiones. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

Solubility
Miscible with dichloromethane, dimethyl formamide, dioxane, terahydrofuran, polar and aprotic organic solvents.

Notes
Moisture sensitive. Incompatible withstrong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 68957-94-8
• Molecular Formula: C9H21O6P3
• MDL Number: MFCD00006583
• InChI Key: PAQZWJGSJMLPMG-UHFFFAOYSA-N
• PubChem CID: 111923

• Density: 1.08
• Boiling Point: 77°C
• Flash Point: −3°C (26°F)
• Refractive Index: 1.419
• Quantity: 50 g
• UN Number: UN2924
• Beilstein: 5079255
• Sensitivity: Moisture sensitive
• Synonym: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide, 1-propanephosphonic acid cyclic anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide, unii-i6egd8839n, 1,3,5,2,4,6-trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide, propane phosphonic acid anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane 2,4,6-trioxide, 1-propanephosphonic anhydride in thf, 2,4,6-tri-n-propyl-2,4,6-trioxo-1,3,5,2,4,6-trioxatriphosphorinane, 1-propanephosphonic anhydride in toluene, t3p
• Solubility Information: Miscible with dichloromethane,dimethyl formamide,dioxane,terahydrofuran,polar and aprotic organic solvents.
• SMILES: CCCP1(=O)OP(=O)(OP(=O)(O1)CCC)CCC
• IUPAC Name: 2,4,6-tripropyl-1,3,5,2$l^{5},4$l^{5},6$l^{5}-trioxatriphosphinane 2,4,6-trioxide
• Molecular Weight (g/mol): 318.182
• Formula Weight: 318.19
• Concentration or Composition (by Analyte or Components): ≥50% soln. in ethyl acetate
• Chemical Name or Material: 1-Propylphosphonic acid cyclic anhydride

Safety and Handling

Hazard Category	H225-H314-H335-H336
Hazard Statement	GHS H Statement H225-H314-H336 Highly flammable liquid and vapor. Causes severe skin burns and eye damage. May cause drowsiness or dizziness.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber	422-210-5
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only