1-Propylphosphonic acid cyclic anhydride, 50+% w/w soln. in dichloromethane, Thermo Scientific Chemicals

Description

1-Propylphosphonic acid cyclic anhydride is used as a reagent for amide/peptide bond formation. It is utilized for condensation reactions and alcohol oxidations. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Propylphosphonic acid cyclic anhydride is used as a reagent for amide/peptide bond formation. It is utilized for condensation reactions and alcohol oxidations. It is also used to promote the synthesis of hydroxamic acids from carboxylic acids. Further, it is employed as an efficient promoter for the Lossen rearrangement to synthesis urea and carbamate derivatives.

Solubility
Miscible with dioxane, terahydrofuran, dimethyl formamide, polar and aprotic organic solvents.

Notes
Moisture sensitive. Incompatible withstrong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 68957-94-8
• Molecular Formula: C9H21O6P3
• Molecular Weight (g/mol): 318.182
• MDL Number: MFCD00006583
• InChI Key: PAQZWJGSJMLPMG-UHFFFAOYSA-N
• Synonym: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide, 1-propanephosphonic acid cyclic anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide, unii-i6egd8839n, 1,3,5,2,4,6-trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide, propane phosphonic acid anhydride, 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane 2,4,6-trioxide, 1-propanephosphonic anhydride in thf, 2,4,6-tri-n-propyl-2,4,6-trioxo-1,3,5,2,4,6-trioxatriphosphorinane, 1-propanephosphonic anhydride in toluene, t3p
• PubChem CID: 111923
• IUPAC Name: 2,4,6-tripropyl-1,3,5,2$l^{5},4$l^{5},6$l^{5}-trioxatriphosphinane 2,4,6-trioxide
• SMILES: CCCP1(=O)OP(=O)(OP(=O)(O1)CCC)CCC

• Quantity: 10 g
• UN Number: UN2922
• Beilstein: 5079255
• Solubility Information: Miscible with dioxane,terahydrofuran,dimethyl formamide,polar and aprotic organic solvents.
• Formula Weight: 318.19
• Concentration or Composition (by Analyte or Components): ≥50% w/w soln. in dichloromethane
• Chemical Name or Material: 1-Propylphosphonic acid cyclic anhydride

Safety and Handling

Hazard Category	H314-H335-H336-H350
Hazard Statement	GHS H Statement H314-H351 Causes severe skin burns and eye damage. Suspected of causing cancer.
Precautionary Statement	P201-P202-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUIDS, TOXIC, N.O.S.
EINECSNumber	422-210-5
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only