Cayman Chemical 10-acetyl Docetaxel 50mg

Supplier:  Cayman Chemical 3449750 MG

An inhibitor of ASBT (IC50s 0.53 0.13 and 5.8 nM for the human mouse and canine transporters respectively) selective for ASBT over the hepatic sodium/bile acid cotransporter (IC50 240 nM) induces mild giant migrating contractions in the colon and increases the number of defecations in conscious dogs two hours after administration of 3 10 or 30 mg/kg doses as well as increases the number of defecations after ten hours at 30 mg/kg reduces methionine- and choline-deficient diet-induced increases in serum bile acid levels and hepatic inflammation fibrosis and cytokine gene expression in a mouse model of NASH at 1.2 mg/kg per day

Catalog No. 50-295-0252