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Medchemexpress LLC 10-hydroxydecanoic acid | 1679-53-4 | MFCD00010510 | 99.8% | 188.26 g/mol | C10H20O3 | 1mL
Supplier: Medchemexpress LLC HYY014810MM/1ML
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid which can be isolated from royal jelly 10-Hydroxydecanoic acid exhibits various biological activities including anti-inflammatory insecticidal anti-malarial and anti-Leishmania properties as well as enhancing antigen-specific immune responses The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF- B and the translation of interferon regulatory factor 1 (IRF-1) which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells Additionally 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway Finally 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5]
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