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Cayman Chemical 10 ZHeptadecenoIc ACD meth
SDP

Supplier:  Cayman Chemical 26869100 MG

Encompass_Preferred

A histamine H1 receptor antagonist (Ki 1.3 nM) selective for histamine H1 over H2 and H3 receptors (Kis 49 and 12.43 UM respectively) as well as a1- a2- and B1-adrenergic and dopamine D1 and D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1 and 5-HT2 at 10 UM inhibits histamine-induced phosphoinositide turnover and intracellular calcium mobilization in primary HCECs (IC50s 1.6 and 2.9 nM respectively) inhibits histamine-stimulated secretion of IL-6 IL-8 and GM-CSF by primary HCECs (IC50s 2.23 3.42 and 1.50 nM respectively) ocular application of emedastine prior to histamine challenge inhibits vascular permeability in guinea pigs

Catalog No. 50-293-2769


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