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Cayman Chemical 11-DehydrocortIcosteron 10mg
Supplier: Cayman Chemical 3290710 MG
An endogenous mineralocorticoid; increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner; decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of carbenoxolone-induced 11β-hydroxysteroid dehydrogenase inhibition; chronic administration increases plasma glucocorticoids levels, body weight gain, and adiposity, as well as induces insulin resistance in mice
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