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Cayman Chemical 11dehydro Thromboxn B2 ACh

Supplier: Cayman Chemical 419510100 DTN
A pan FGFR inhibitor (IC50s 0.9 1.4 and 1 nM for FGFR1 FGFR2 and FGFR3 respectively) suppresses proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s 5 30 32 and 15 nM for RT112 RT4 SW780 and JMSU1 cells respectively) inhibited tumor growth in an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3 at 10-30 mg/kg
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