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Cayman Chemical 11dehydro Thromboxn B2 ELI 480

Supplier: Cayman Chemical 519510480 WELL

A 5-HT2A 5-HT2B and 5-HT2C receptor agonist induces calcium accumulation in CHO-K1 cells expressing 5-HT2A 5-HT2B or 5-HT2C receptors (EC50s 309.03 177.83 and 338.84 nM respectively for the human receptors) binds to the 5-HT3 receptor (Ki 2.1 nM) decreases food intake in rats at 2.5 5 or 10 mg/kg restores spinal circuitry function improves gait regularity and increases interlimb coordination and limb weight-bearing in a rat model of spinal cord transection-induced hindlimb paralysis at 0.3 mg/kg per day in combination with 8-hydroxy DPAT electrode stimulation of dorsal and lumbar spine regions and locomotor training
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