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Cayman Chemical 11R 12S-EET 100UG
Supplier: Cayman Chemical 9004344100 UG
An oxylipin and a metabolite of arachidonic acid; activates KCa1.1/BK in isolated rat coronary small arterial smooth muscle cells at 50 nM; binds to isolated guinea pig monocytes in a competitive binding assay using [3H]14(15)-EET (Ki = 595.1 nM); inhibits ENaC in a patch-clamp assay using isolated rat cortical collecting duct tubules at 100 nM; induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 6.3 pM) and denuded porcine subepicardial arterioles (EC50 = 1.6 pM); induces migration of HUVECs at 5 µM
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