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Medchemexpress LLC 11R-VIVIT (cell permeable NFAT inhibitor) | 592517-80-1 | 99.6% | 3573.15 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP14305MG

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11R-VIVIT is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It is suitable for the research of podocyte and diabetic nephropathy.

  • Significantly reduces NFAT2 expression in high glucose-treated podocytes
  • Attenuates high glucose-induced filtration barrier dysfunction of podocytes
  • Abrogates increased urinary albumin excretion rates
  • Attenuates glomerular basement membrane (GBM) thickening and podocyte foot process effacement
  • Partially restores podocyte number
  • Inhibits NFAT2 activation and uPAR expression in glomerular podocytes

Catalog No. 50-004-24576


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