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Cayman Chemical 12-keto LIthocholIc AcId 10mg

Supplier: Cayman Chemical 2954710 MG
A metabolite of DCA; fecal levels are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol, HDCA, or LCA; activates the human PXR (EC50 = 31.3 μM in a cell-based transactivation assay); levels are increased in duodenal bile from patients with type 2 diabetes
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