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Cayman Chemical 12-TrIdecenoIc AcId 50mg

Supplier: Cayman Chemical 3760150 MG

A Y-secretase inhibitor selectively cleaves APP CTF over Notch-1 CTF in HEK293 cells (IC50s 7.1 and 105.9 nM respectively) reduces increases in AB42 levels induced by AB (25-35) in the mouse hippocampus at 0.1-1 nmol/animal prevents deficits induced by AB (25-35) in the novel object recognition test when tested with a one-hour but not a 24-hour intertrial interval
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