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Cayman Chemical 12S 13R-EpODE500ug

Supplier: Cayman Chemical 35863500 UG

A Factor D inhibitor (IC50 15 nM in a cell-free assay) selective for Factor D over a panel of 12 serine proteases when used at a concentration of 10 UM inhibits hemolysis of erythrocytes isolated from patients with paroxysmal nocturnal hemoglobinuria (IC50s 4-27 nM) suppresses APC activity in monkeys at 200 mg/kg p o
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