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Enzo Life Sciences 12(S)-Hydroperoxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (HPETE) (50µg). CAS: 71774-10-2

Supplier: Enzo Life Sciences BMLHP0120050

Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM). Alternative name: 12(S)-HPETE. Formulation: Solution in ethanol. Purity: ≥98%. Solubility: Soluble in DMSO or dimethyl formamide; slightly soluble in PBS, pH 7.2 (0.8mg/ml) or 0.1M Na2CO3 (2mg/ml). Long Term Storage: -80°C.
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