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Cayman Chemical 13 Z-EIcosenoIc AcId 10mg

Supplier: Cayman Chemical 2616910 MG

An orally bioavailable mPGES-1 inhibitor (IC50 3 nM) selective for mPGES-1 over PGDS TXAS and 5-LO in HWB-1483 cells which have IC50 values 50 M as well as COX-2 in fetal fibroblasts (IC50 10 M) inhibits LPS-stimulated synthesis of PGE2 in human whole blood (IC50 109 nM) inhibits PGE2 production in a guinea pig model of carrageenan-induced air pouch inflammation (10 mg/kg)
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