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Medchemexpress LLC 14-Deoxy-11,12-didehydroandrographolide | 42895-58-9 | MFCD07778081 | 332.43 | 100 MG
Supplier: Medchemexpress LLC HYN1490100MG
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. It inhibits NF-κB activation.
- An analogue of Andrographolide.
- Inhibits NF-κB activation.
- Reduces ovalbumin (OVA)-induced inflammatory cell recruitment into bronchoalveolar lavage (BAL) fluid, IL-4, IL-5, IL-13, eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion, mast cell degranulation, and airway hyper-responsiveness (AHR) in a mouse asthma model.
- At 1 mg/kg, it dramatically reduces resistance (Rl) and restores Cdyn in OVA-challenged mice in response to methacholine.
- Appearance: Solid.
- Color: White to light yellow.
- Purity: 99.93%.
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