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Enzo Life Sciences 1400W . dihydrochloride (25mg). CAS: 214358-33-5
SDP

Supplier:  Enzo Life Sciences ALX270073M025

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A slow, tight binding and highly selective inhibitor of inducible nitric oxide synthase (iNOS/NOS II) in vitro and in vivo. Binds tightly to iNOS with a Kd of 7nM. In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Ki values of 2 and 50µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices. Formula: C10H15N3 . 2HCl. MW: 177.3 . 73.0. Purity: ≥95% (TLC). Appearance: White to off-white powder. Solubility: Soluble in water (up to 25mg/ml), methanol or DMSO. Long Term Storage: -20°C. Handling: Hygroscopic.

Catalog No. 50-200-8399


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