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Cayman Chemical 1400WhydrochlorIde 10mg
Supplier: Cayman Chemical 8152010 MG
1400W is a potent, selective inhibitor of iNOS.{4277} Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively.{4277} In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS.{4277} In mice bearing a murine mammary carcinoma, continuous infusion of 1400W at a rate of 10 mg/kg for 6 days decreased tumor weight approximately 50% compared to controls.{5066}
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