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Cayman Chemical 15mthyl PalmItIc ACD mthy 10mg
SDP

Supplier:  Cayman Chemical 2481510 MG

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An insecticide and GABAA receptor antagonist inhibits GABA-stimulated chloride uptake by membrane vesicles from rat cerebral cortex (IC50 68 M) binds selectively to insect GABAA receptors over mammalian GABAA receptors in membrane preparations (IC50s 1 12 505 833 150-1 675 nM for fruit fly house fly human mouse and rat respectively) a human recombinant B3 homooligomer with similar selectivity as a1B3Y2-containing receptors indicating that the binding site for Y-lindane on GABAA receptors is located on the B3 subunit (IC50s 0.90 21 and 306 nM for B3 a1B3Y2 and the native receptor respectively) blocks GABA- and glutamate-induced current responses in American cockroach neurons (IC50s 1.74 and 148 nM respectively) toxic to mice and adult house flies (LD50s 40 and 5.5 mg/kg respectively) kills head lice in vitro and inhibits hatching

Catalog No. 50-301-6003


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