Sorbitol MacConkey (sMAC) Agar, also known as MacConkey Agar with Sorbitol, is a selective and differential medium used for the isolation of sorbitol-negative Escherichia coli. March and Ratnam introduced sMAC in 1986 for the isolation of verotoxin-producing (VTEC) Escherichia coli O157:H7 from clinical specimens. VTEC does not ferment sorbitol (i.e. - sorbitol-negative), while non-VTEC Escherichia coli are sorbitol-positive. Further identification and/or epidemiological typing should be performed on suspect colonies.• Product meets BAM, CLSI, ISO, and SMWW reference methods and performance criteria.• sMAC should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.