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17-(Allylamino)-17-demethoxygeldanamycin, 99%
Description
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Specifications
Specifications
Melting Point | 207°C to 209°C |
Flash Point | >110°C (230°F) |
Quantity | 100 mg |
Sensitivity | Light sensitive |
Solubility Information | Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/ml; Very poorly soluble in water |
Formula Weight | 585.69 |
Percent Purity | 99% |
Physical Form | Solid |
Chemical Name or Material | 17-(Allylamino)-17-demethoxygeldanamycin |
Safety and Handling
RTECSNumber | LX8932000 |
TSCA | No |
storageNote1 | -30° to -10°C |
Recommended Storage | Store at -20°C |
RUO – Research Use Only
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