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MP Biomedical™ 17α-Hydroxyprogesterone Double Antibody RIA Kit

Catalog No. MP07171102 Shop All MP Biomedicals, Inc Products
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500 Tubes
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MP07171102 500 Tubes
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Description

Quantitative Liquid Phase Radioimmunoassay

The 17αHP Double Antibody RIA Kit is intended for the measurement of 17α-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17α-hydroxyprogesterone (17αHP) is produced by both the adrenal cortex and gonads. Even though 17αHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17αHP, measurement of 17αHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17αHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17αHP is therefore valuable in the initial diagnosis of CAH.
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Specifications

Product Type Kit and Assay
Sample Type Plasma, Serum
Target Species Human
For Use With (Application) Endocrinology
Quantity 500 Tubes
Regulatory Status FDA Cleared (K840886)
Sample Volume 25 μL
Storage Requirements 2°C to 8°C

Safety and Handling

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