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Drg International Inc DRG 17-OH Progesterone ELISA, 96 Well Kit
Supplier: Drg International Inc EIA1292
An enzyme immunoassay for the quantitative measurement of 17-Alpha-OH progesterone (17-Alpha-OHP) in serum or plasma. The steroid 17-Alpha-Hydroxyprogesterone (17-Alpha-OHP) is produced by both the adrenal cortex and gonads. Even though 17-Alpha-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-Alpha-OHP, measurement of 17-Alpha-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-Alpha-OHP is secreted in abundant excess. The DRG 17-OH Progesterone ELISA Kit is a solid phase enzyme-linked immunosorbent assay (ELISA), based on the principle of competitive binding. The microtiter wells are coated with a polyclonal [rabbit] antibody directed towards an antigenic site of the 17-Alpha-OHP molecule.
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