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Cayman Chemical 17a-Hydroxyprogesteron 10g
Supplier: Cayman Chemical 3315410 G
A steroid and precursor in the synthesis of adrenal androgens; binds to the glucocorticoid receptor in a cell-free assay (IC50 = 82 nM for the human receptor) and induces glucocorticoid receptor transactivation in HEK293 cells (EC50 = 1.2 µM); inhibits aldosterone-induced transactivation of the mineralocorticoid receptor in cell-based assays from 0.005-1 µM; serum levels are increased in patients with congenital adrenal hyperplasia
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