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Cayman Chemical 17phenyl trInor PrstglndI 10mg

Supplier: Cayman Chemical 1481010 MG

An inhibitor of Akt1 and Akt2 with anticancer activity inhibits Akt1 and Akt2 in a kinase assay but has no effect on MEK1 JNK1 ERK1 or PBK at 1 UM increases apoptosis in HCT116 and HT-29 colon cancer cells at 4 UM inhibits growth of HCT116 cells in vitro reduces tumor growth in an HCT116 mouse xenograft model at 30 mg/kg decreases status epilepticus-induced vasogenic edema and reduces increases in eNOS levels in the piriform cortex in rats at 25 UM
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