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Medchemexpress LLC 18β-Glycyrrhetinic acid | 471-53-4 | 99.88% | 470.68 | 5 G
Supplier: Medchemexpress LLC HYN01805G
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and Glycyrrhizae Radix, known for its anti-ulcerative, anti-inflammatory, and antiproliferative properties. In vitro studies show it suppresses cell proliferation in a dose-dependent manner and influences PARP levels. In vivo, low-dose administration has demonstrated hepatoprotective effects against Triptolide-induced lesions and suppresses cytokine release.
- Exhibits anti-ulcerative, anti-inflammatory, and antiproliferative properties
- Suppresses cell proliferation in various cell lines in a dose-dependent manner
- Decreases full-length PARP levels and increases cleaved-PARP levels
- Demonstrates hepatoprotective effects against Triptolide-induced lesions in rats
- Suppresses cytokine release in animal models
- Applicable for cell assays with primary microglia cultures
- Suitable for animal administration studies
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