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Medchemexpress LLC 18-hydroxy-11-deoxy corticosterone | 379-68-0 | 346.46 | C21H30O4 | 1mg
Supplier: Medchemexpress LLC HYW7386391MG
18-Hydroxy-11-deoxy corticosterone (18-OH-DOC) is a mineralocorticoid whose synthesis is regulated by adrenocorticotropic hormone (ACTH) and angiotensin II 18-Hydroxy-11-deoxy corticosterone is an intermediate in the metabolism of progesterone and plays an important role in regulating blood pressure and water-salt balance Continuous infusion of 18-Hydroxy-11-deoxy corticosterone can increase systolic blood pressure in rats and plasma levels of 18-Hydroxy-11-deoxy corticosterone are significantly elevated in the db/db mouse model of type 2 diabetes suggesting its potential involvement in metabolic dysregulation and diabetes-related regulation 18-Hydroxy-11-deoxy corticosterone holds promise for research in areas such as hypertension diabetes and other related fields[1]
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