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Cayman Chemical 1D-2-DeoxyrIbofurnosyl-1 2.3mg
SDP

Supplier:  Cayman Chemical 385622.3 MG

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An inhibitor of RAN translation selectively binds to r(G4C2)8 (EC50 19 UM) over r(G2C4)8 and r(GGCC)10 inhibits RAN translation and the formation of nuclear stress granules in HEK293T cells expressing r(G4C2)66 in an in vitro model of c9ALS/FTD at 25 UM induces relaxation of rat thoracic aortic rings pre-contracted with norepinephrine (EC50 1.81 UM) and decreases systolic arterial pressure in conscious spontaneously hypertensive rats when administered at a dose of 100 mg/kg

Catalog No. 50-291-9132


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