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Cayman Chemical 1D-ArabInofurnosyluracIl 50g

Supplier: Cayman Chemical 2987550 G

An orally bioavailable non-selective calcium channel blocker blocks L- and T-type calcium channels in GH3 rat pituitary cancer cells (IC50s 0 5 and 1 5 g/ml respectively) blocks carbachol- and A23187-stimulated calcium influx in CHO cells expressing human recombinant M5 receptors (IC50s 935 and 359 nM respectively) inhibits the growth of T gondii in non-cancerous human fibroblasts and HeLa human cervical cancer cells (IC50 0 06 g/ml for both) inhibits the growth of human FaDu and EVSCC17M squamous cell carcinoma cells (IC50s 13 and 15 M respectively) and of HUVECs (IC50 1 M) inhibits angiogenesis in a chicken chorioallantoic membrane assay in vivo at 20 M
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