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Medchemexpress LLC 1H-1,2,3-Triazole, 1-(3-iodophenyl)-4-(3-nitrophenyl)- | 1809031-84-2 | 99.5% | 392.15 | 10 MG

Supplier: Medchemexpress LLC 10MGHY115576
P62-mediated mitophagy inducer (PMI) is a P62-mediated mitophagy activator that activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential. It remains active in cells lacking a fully functional PINK1/Parkin pathway and serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential.
- P62-mediated mitophagy activator
- Activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential
- Remains active in cells lacking a fully functional PINK1/Parkin pathway
- Serves as a pharmacological tool to study the molecular mechanisms of mitosis
- Avoids toxicity and some non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential
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