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Medchemexpress LLC 1H-Benzimidazole, 2-methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]- | 93987-29-2 | 99.9% | 331.35 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10846910MM/1ML

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BI-6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that inhibits the expression of known HNF4α target genes. It represses insulin promoter activity through HNF4α antagonism and can be used for the research of cancer and diabetes.

  • HNF4α antagonist
  • Inhibits expression of known HNF4α target genes
  • Represses insulin promoter activity through HNF4α antagonism
  • Can be used for research of cancer and diabetes
  • Cytotoxic to human hepatocellular carcinoma
  • Induces hepatic steatosis in primary murine hepatocytes
  • Induces loss of HNF4α expression and hepatic steatosis in mice
  • Induces apoptosis in a human hepatocellular carcinoma mouse model
  • Inhibits HNF4α gene expression in HepG2 cells

Catalog No. 50-003-47172


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