Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000415258

Medchemexpress LLC 1H-Indole-3-methanol, 1-(phenylmethyl)- | 60941-76-6 | 237.30 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN101595MG

Encompass_Preferred

1-Benzyl-I3C is an E1/E2/E3 enzyme inhibitor, specifically a NEDD4-1 inhibitor, demonstrating significant anticancer activity. It directly inhibits the ubiquitination activity of NEDD4-1 with an IC50 of 12.3μM, which is considerably more potent than its precursor compound I3C. In vitro ubiquitination experiments and thermal stability analysis indicate that 1-Benzyl-I3C binds to the catalytic HECT domain of NEDD4-1. This product is for research use only.

  • Inhibits E1/E2/E3 enzymes
  • Shows significant anticancer activity
  • Binds to the catalytic HECT domain of NEDD4-1
  • High purity of 99.68%
  • White to off-white solid appearance

Catalog No. 50-004-15258


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.