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Medchemexpress LLC 1h-pyrrole-2,5-dione, 1-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)- | 1262681-30-0 | 99.7% | 311.33 | 25 MG
Supplier: Medchemexpress LLC 25MGHY140037
Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with molecules containing azide groups
- Appearance: Colorless to light yellow oil
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