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Cayman Chemical 1MyrIstoyl3Oleoylracglyc 50mg
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Supplier:  Cayman Chemical 2688650 MG

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An inhibitor of the Dvl PDZ domain (Kd 240 M for mouse Dvl1 PDZ domain) reduces expression of the Wnt target gene Siamois in Xenopus embryos and inhibits the ability of injected Wnt3A to induce formation of a secondary axis (180 ng) inhibits proliferation of NIH/3T3 fibroblasts restrains their migration in a scratch assay and blocks the accelerating effect of TGF-B on fibroblast migration (10 M) reduces the severity of bleomycin-induced pulmonary fibrosis and expression of a-SMA collagen I TGF-B andBcatenin in lung in mice (5 mg/kg per day for 14 days)

Catalog No. 50-293-4906


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