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Medchemexpress LLC ((1R,2S,4R)-4-((5-(1-(3-bromobenzyl)-1H-pyrazole-3-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate | 1644342-14-2 | 99.8% | 551.41 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY108702100MG

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ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays with IC50 values of 3 and 11 nM, respectively. It shows significantly less activity against NAE/NEDD8 and UAE/ubiquitin. This compound inhibits SAE and SUMO-pathway activities in HCT116 cells, and decreases cancer cell viability in various cancer cell lines. This compound is for research use only.

  • Potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2.
  • Inhibits SAE and SUMO-pathway activities in HCT116 cells.
  • Inhibits cell proliferation and decreases cancer cell viability in various cancer cell lines (MDA-MB-468, MDA-MB-231, HCT116, Colo-205, and A375).

Catalog No. 50-003-46386


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