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Medchemexpress LLC 2-[2,2-di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine | 1190197-97-7 | MFCD31813697 | 99.9% | 642.09 g/mol | C43H79NO2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1127585MG

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DLin-KC2-DMA is an ionizable cationic lipid used to formulate lipid nanoparticles (LNPs) for siRNA and nucleic acid delivery. It has an apparent pKa near 6-6.7 and has been reported to enable significant siRNA-mediated gene silencing while exhibiting low toxicity to antigen-presenting cells.

  • Ionizable cationic lipid with apparent pKa ≈ 6-6.7.
  • Facilitates efficient encapsulation and delivery of siRNA in lipid nanoparticles.
  • Produces significant siRNA-mediated gene silencing in LNP formulations.
  • Low toxicity to antigen-presenting cells, suitable for biological studies.
  • High-purity liquid, colorless to light yellow; compatible with formulation workflows.

Catalog No. 50-002-62466


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